16 replies to this topic

[mind]

struikelde net over een trip reportje bij Bluelight: hier...

verder nog nooit wat over gehoord ofzo, iemand wat op/aanmerkingen of info of iets anders ?

[dreamer]

werkelijk nog NOOIT van gehoord

[Blowmonkey]

Dit is uit een post van Bluelight, dat origineel afkomt van een "ander board".. Komt rechtstreeks van Shulgin:

#xxx 5-METHOXY-DALT; TRYPTAMINE, N,N-DIALLYL-5-METHOXY; N,N-
DIALLYL-5-METHOXYTRYPTAMINE; INDOLE, 3-[2-(DIALLYLAMINO)ETHYL]-5-
METHOXY; 3-[2-(DIALLYLAMINO)ETHYL]-5-METHOXYINDOLE

SYNTHESIS: Synthesis section removed by moderator. Wait for the book and buy it!

DOSAGE: 12 - 20 mg. orally

DURATION: 2 - 4 h

QUALITATIVE COMMENTS (from various sources): (with 10 mg. orally)
"I am looking at everything through someone's open friendly eyes,
not mine. I would like to go through life like this if others
saw me as OK. I am 10 feet tall, my pulse is 72 but uneven, and
light-headed is a better describer of where I am than
psychedelicized."

(with 16 mg. orally) "The music was fabulous, as was the sex and
neither of us had a problem with orgasm. But there was a total
lack of imagery -- less than I would normally have to the music
when unstoned, so there might have been an actual suppression. I
was pretty much baseline by the third hour."

(with 20 mg. orally) "It's coming on strongly in 15 minutes, and
at the half hour point I am at a +++ with eyes closed -- but
nothing with them open! No hang-over."

EXTENSIONS AND COMMENTARY: The rapid onset and rapid drop-off of
5-MeO-DALT is remarkable. With oral administration, it is common
to be aware of the effects in less than 15 minutes and to be
fully there at the half-hour point. This implies absorption into
the blood stream directly from the stomach and rapid metabolic
destruction.

To my total suprise, this compound is not in the scientific
literature, at least as searched by Chem. Abstracts. Its
synthesis and its pharmacology have never been published.

There are a number of modifications of the two double bonds
ont there on the nitrogen alkyl groups that would be interesting
to explore. If they were changed from double bonds to triple
bonds, one would have 5-methoxy-N,N-dipropargyltryptamine, or 5-
MeO-DPRT. I have made a little bit of it but it was quite impure
and difficult to clean up. The complexity of the GCMS patterns
suggested that there might be some chemistry going on between the
two propargyl groups.

Another direction possible for modifying the structure
would be to relocate the oxygen in indole ring over to the 4-
position. 4-Methoxytryptamine is commercially available, and it
should be directly substitutable for the 5-methoxytryptamine used
in this synthetic process giving rise to 4-MeO-DALT. Yet further
out, what about starting the 4-benzyloxytryptamine and walking
the same path? The product could be easily stripped of the
benzyl ether by the usual catalytic hydrogenation, giving rise to
the diallyl analogue of psilocin, 4-HO-DALT. I would wager a ten
dollar bet that the acetate ester of this material, 4-AcO-DALT
would be in the brain within minutes of swallowing the pill.

There are a lot of interesting extensions, but all of them
would call for careful chemistry. And, of course, the essential
care of tasting new things in very small increasing doses. Some
of these could be extremely potent.

[ksi]

Kwam het net ook tegen, wel interesting.

En thanks voor die post blowmonkey, interesting. Is dat een stukkie uit tihkal!?

[dreamer]

Is dat een stukkie uit tihkal!?

Nope, heb ik van binnen en van buiten gelezen :book: : no 5-meo-DALT

Ik zou graag de structuurformule willen zien. Ik kan zo ff niet bedenken wat een 'ally' ook alweer is


[edit: ik bedoelde STRUCTUURformule ]

[mind]

Is dat een stukkie uit tihkal!?

stukje uit zijn nieuwe boek dacht ik, staat ook bij de post van blowmonkey.

thanks for posting monkey !

[Blowmonkey]

Komt uit z'n nieuwe boek, forwarded naar Murple, wat dus eigenlijk "top-secret" moest blijven, totdat het werd gepost op Bluelight..

Hier zijn de structuurformules van DALT en 5-MeO-DALT:

[Blowmonkey]

Trouwens, er was ook nog iemand anders die dit had uitgeprobeerd rond de ~20, ~30 en ~40 mg, die niet veel meer rapporteerde dan een aardig sterke +2/+3 op de 40 mg, die met wat onaangename bodyload (e.g. 5-MeO-DiPT verschijnselen, ouch!) te kampen had. De ervaring deed hem denken aan een combinatie van 5-MeO-DiPT en 5-MeO-DMT, maar echt psychedelisch kan hij het niet noemen. de 20 en 30 mg deden niet echt veel bij hem.

Beware and beware! Doe rustig aan als je besluit dit te kopen en te nuttigen, je bent een van de eersten..

[dreamer]

pfft, als ik het zo hoor hoef ik het iig niet

[wittig]

En hier is ook nog DALT: (dus zonder die methoxy groep op de 5e positie van de indole ring)

#xxx DALT; TRYPTAMINE, N,N-DIALLYL; N,N-DIALLYLTRYPTAMINE;
INDOLE, 3-[2-(DIALLYLAMINO)ETHYL]; 3-[2-(DIALLYLAMINO)ETHYL]-
INDOLE

SYNTHESIS: To a solution of 1.60 g. tryptamine (10 mM) in 25 mL
tetrahydrofuran, there was added 5.2 mL diisopropylethylamine and
2.72 mL allyl iodide (30 mM). The solution (which became cloudy
in 20 minutes) was stirred at ambient temperature for 12 hrs.
The dark red solids that formed were broken up mechanically and,
after they had settled, the overhead liquid was removed by
decantation. The remaining solids were washed with 30 mL
anhydrous ether, and these washings were combined with the
decanting and the volatiles were removed on the rotary
evaporator. The crude isolate was dissolved in 1.0 mL pyridine
and treated with 1.0 mL acetic anhydride, heated on the steam
bath for 0.5 h., diluted with 40 mL 0.5 N. aq. HCl and washed
with three 25 mL portions of methylene chloride. The aqueous
fraction was made basic with 5% aq. NaOH, extrtacted with three
25 mL portions of methylene chloride which were combined and the
solvent removed on the rotary evaporator. The residue (0.68 g.)
was distilled at the KugelRohr (b.p. 155-165 C., 40 microns) to
yield 0.21 g. of a nearly colorless oil that spontaneously
crystallized in the receiver. This was dissolved in 2.0 mL
isopropanol, treated with conc. HCl dropwise until the solution
was acidic to external damp pH paper (about seven drops required)
and diluted with 10 mL anhydrous ether which produced, with
scratching, fine powdery crystals. These were removed by
filtration, washed with ether, and allowed to air-dry to constant
weight. There was thus obtained 0.174 g of the first crop of
N,N-diallyltryptamine hydrochloride (DALT). GCMS indicated a
purity of >99%, and fragmenets (m/z): 110 (diallylaminomethylene
fragment 100%), 130 (3-indolemethylene fragment, 15%), 199 (1%)
and 240 (parent, 1%). The infra-red spectrum contained the
following major peaks (cm-1): 750, 767, 801, 940, 952 and 1106.
The m.p. was 142-143 C.
The solids that remained following the above decantations
were thoroughly titurated under 25 mL methylene chloride and the
remaining white powder removed by filtration, washed generously
with methylene chloride and air-dried to constant weight. The
white solid weight (3.74 g.) had an infra-red spectrum consistent
with the quatenary salt N,N,N-triallyltryptammonium iodide (cm-
1): 753, 950, 980, 991, 1011, 1090, 1100. LCMS indicated a
cation with a molecular weight of 281. Removal of the solvent
from the mother liquors provided 5.10 g. of a yellow-tan solid
that had an infra-red spectrum identical to that of a reference
sample of diisopropylethylamine hydriodide.
To a solution of 1.1 g. phenylmercaptan (10 mM) in 20 mL
acetone, there was added 0.4 g. 50% W/W NaOH (5 mM) followed by
2.04 g. of N,N,N-triallyltryptammonium iodide (5 mM) and the
mixture held at reflux on a steam bath for 12 hr. After removal
of all volatiles on the rotary evaporator, the residue was
suspended in 75 mL water and made acidic with the addition of aq.
HCl. This was washed with 2x40 mL methyene chloride (the
washings were saved), made basic with 5% NaOH, and extracted with
3x40 mL methylene chloride. The combined extracts were stripped
of solvent on the rotary evaporator yielding 0.354 g. of a pale
yellow oil which crystallized. Distillation at the KugelRohr
yielded 0.13 g of a white oil which as converted to the DALT
hydrochloride salt (as above) weighing 0.10 g. The methylene
chloride washings above, on removal of the solvent, yielded a
small amount of a brown oil (additional diallyltryptamine) and a
clear colorless fluid that set to a spectacular crystalline mass
of diphenyldisulfide.

DOSAGE: >40 milligrams orally.

DURATION: unknown

QUALITATIVE COMMENTS:

EXTENSIONS AND COMMENTARY: As far as I can determine, there has
only been a single human trial of DALT mentioned in the published
clinical literature. This was by Dr. Stephen Szara long ago,
in 1960 plus or minus a year or two. Most of the literature
papers that make reference to N,N-diallyltryptamine are reviews
of the structure-activity relationships of the psychedelics, and
thus they do not present any new human data. It is an
interesting trip to work backwards from these reviews to the
original statements that were made.
Most listed potencies are based on the generalization
that the activity of DALT was similar to that of DMT. Thus when
DMT is listed at 60 milligrams, this number appears as the
potency of DALT. And if the range of 60-100 milligrams is given
for DMT, then DALT is often stated to be at the mid-point, or 80
milligrams. I must apologize in that I am equally guilty of just
this kind of sloppy bookkeeping. All this is somewhat supported
superficially by the numbers in a chapter that Szara published in
1970 in Efron's "Psychotomimetic Drugs." In Figure I, there is
stated that a psychotropic dose of diallyltryptamine was "60 mg
i.m. or p.o." but the drug is not mentioned in the text or the
discussion. The yet earlier (and first) text mention of DALT is
in a paper by Szara and Hearst in 1962 (Annals of the New York
Academy of Science, 96 pp 134-142). There it is stated: "As
reported by Szara in Milan in 1957, administration of
diethyltryptamine (DET) and dimethyltryptamine (DMT) lead to
rapidly developing sympathomimetic effects , as well as to
perceptual, emotional and thinking disturbances similar to those
that result after administration of LSD-25 or mescaline. However
the psychological effects persist for only 1 hour in the case of
DMT and for about 2.5 hours in the case of DET; in contrast LSD
and mescaline have a much longer (6 to 8 hour) duration." There
is then added the short phrase, "The dipropyl and diallyl
derivatives have similar activities in man, as we found
recently." I finally found the Milan report of Szara: it is in
"Psychotropic Drugs," edited by Garattini and Ghetti (Elsevier,
1957). There, he describes four personal experiences: Three are
with DMT at 60, 60 and 75 milligrams, all i.m. and one was with
DET (also called T-9) at 60 milligrams, i.m. No mention is made
of diallyltryptamine.
So, the early and only discovery report of DALT mentioned
neither the synthetic preparation, the dosage taken, the route of
administration, nor the effects observed. It merely stated that
the activity had been found. I have explored it up to 42
milligrams, I was to a +1 in an hour, back to base line at the
fourth hour, and there was nothing that caught my fancy.

[Cad0]

Wow, dit is werkelijk zeer interessant! Ik ben benieuwd naar wat er volgen zal!

There are a lot of interesting extensions, but all of them would call for careful chemistry. And, of course, the essential care of tasting new things in very small increasing doses. Some of these could be extremely potent.

[myx0r]

iemand dit inmiddels al eens geprobeerd?

[tms]

Ik heb een paar dosissen liggen, binnenkort maar eens aan wagen..

[ErnstJünger]

Na een tijdje al het huiselijk stof vergaard te hebben, toch maar het zakje 5-MeO-DALT opgediept. Juist vanwege zijn zeer korte werking (2-4u) geschikt voor overwerkte worker bees.

Begonnen met de voorgeschreven TiHKAL² dosis (12-25mg) op een lege maag, maar dat was een algehele teleurstelling. Geheel in lijn met al die andere teleurgestelde trials die op het net circuleren.

Dit weekeinde de dosis opgeschroefd en voor nasaal gegaan.
50mg is een redelijke dosis met voornamelijk een body high gelijkaardig aan die van MDMA. Op mentaal vlak geen verbazende processen, gewoon een algehele Gemütlichkeit. Eroticiteit factor 10
Gisteren 78mg gesnoven, maar dat voegde niets nieuws toe aan de trip qua beleving.

Wat blijkt: net zoals bij vele tryptamines in TiHKAL vind ik de voorgeschreven dosis wel heel laag. Vanaf 50mg wordt deze écht wél interessant.
De curve is dus niet zo stijl en zelfs na een hoge dosis kan je nog altijd makkelijk slaap vatten na 5u.

Ook wat interessante reports gelezen van het na vaporizen, wat dan een über-DMT visuele trip zou geven. Da's voor later...

Interessant stofje als gateway drug, of voor recreatieve weekdagen

Hoe dan ook één van de weinige tryptamines die eetlust stimuleren.

[Phlogiston]

Weet iemand of het vergelijkbaar is met (5-MeO)-DPT??


Persoonlijk ben ik niet zo'n fan van een allyl-functie in de structuur, omdat deze toch enigerwijs reactief kunnen zijn en daardoor carcinogenic of mutanogenic kunnen zijn, dit is wel een vooroordeel, want deze verbindingen zijn daar nog niet goed genoeg voor getest, maar tot die tijd zal ik (5-MeO)-DALT, AL-LAD, enz. links laten liggen.

[ThijsWTF]

Zijn hier inmiddels meer ervaringen mee? Ik kan het krijgen in pellets van 40mg en vraag me af wat ik kan verwachten van zo'n dosis.

[Paulov]

Ben er ook over aan lezen en vroeg me af of er al nieuwe ervaringen zijn?