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Psychedelic Drugs in BiomedicineTrends in Pharmacological Sciences - Nov 2017

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#1 Phlogiston

Phlogiston

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Posted 23 November 2017 - 01:32 PM

Heel zeer recente review van de ontwikkelingen binnen de "psychedelic sciences".

 

 

Bron: http://www.sciencedi...165614717301608

 

Psychedelic Drugs in Biomedicine

 

Abstract
Psychedelic drugs, such as lysergic acid diethylamide (LSD), mescaline, and psilocybin, exert profound effects on brain and behavior. After decades of difficulties in studying these compounds, psychedelics are again being tested as potential treatments for intractable biomedical disorders. Preclinical research of psychedelics complements human neuroimaging studies and pilot clinical trials, suggesting these compounds as promising treatments for addiction, depression, anxiety, and other conditions. However, many questions regarding the mechanisms of action, safety, and efficacy of psychedelics remain. Here, we summarize recent preclinical and clinical data in this field, discuss their pharmacological mechanisms of action, and outline critical areas for future studies of psychedelic drugs, with the goal of maximizing the potential benefits of translational psychedelic biomedicine to patients.

 


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