Bromantane is een in Rusland ontwikkelde stimulant met enkele unieke eigenschappen. Naast dat het een stimulant is zou het ook een anxiolotic zijn. Daarnaast is het mechanisme van bromantane anders dan die van de "klassieke" stimulantia zoals amfetamine. De Engelse wikipedia zegt het volgende hierover:
"Although it is frequently labeled as a psychostimulant, bromantane is distinct in its pharmacology and effects relative to typical psychostimulants, such as the phenethylamines (e.g., amphetamine and its derivatives) and their structural analogues (e.g., methylphenidate, cocaine, mesocarb, etc.).[25][26] Whereas the latter directly act on the dopamine transporter to inhibit the reuptake and/or induce the release of dopamine, bromantane instead acts via indirect genomicmechanisms to produce a rapid, pronounced, and long-lasting upregulation in a variety of brain regions of the expression of tyrosine hydroxylase (TH) and aromatic L-amino acid decarboxylase (AAAD) (also known as DOPA decarboxylase), key enzymes in the dopamine biosynthesis pathway.[19][27][28] For instance, a single dose of bromantane produces a 2- to 2.5-fold increase in TH expression in the rat hypothalamus 1.5- to 2-hours post-administration.[29] The biosynthesis and release of dopamine subsequently increase in close correlation with TH and AAAD upregulation.[19][27][28] Enhancement of dopaminergic neurotransmission is observed in the hypothalamus, striatum, ventral tegmental area, nucleus accumbens, and other regions.[19][27][28] As such, the key mechanism of the pharmacological activity and psychostimulant effects of bromantane is activation of the de novo synthesis of dopamine via modulation of gene expression.[27] In contrast, typical psychostimulants do not affect TH or AAAD expression and thus have no effect on dopamine biosynthesis.[26][30]"
Ik verwacht dit middel ergens aankomende week door mijn brievenbus geschoven te krijgen en vroeg mij af of iemand al ervaring heeft met dit middel?